IoT-Based Solution for Paraplegic Sufferer to Send Signals to Physician via Internet

We come across hospitals and non-profit organizations that care for people with paralysis who have experienced all or portion of their physique being incapacitated by the paralyzing attack. Due to a lack of motor coordination by their mind, these persons are typically unable to communicate their requirements because they can speak clearly or use sign language. In such a case, we suggest a system that enables a disabled person to move any area of his body capable of moving to broadcast a text on the LCD. This method also addresses the circumstance in which the patient cannot be attended to in person and instead sends an SMS message using GSM. By detecting the user part's tilt direction, our suggested system operates. As a result, patients can communicate with physicians, therapists, or their loved ones at home or work over the web. Case-specific data, such as heart rate, must be continuously reported in health centers. The suggested method tracks the body of the case's pulse rate and other comparable data. For instance, photoplethysmography is used to assess heart rate. The decoded periodic data is transmitted continually via a Microcontroller coupled to a transmitting module. The croaker's cabin contains a receiver device that obtains and deciphers data as well as constantly exhibits it on Graphical interfaces viewable on the laptop. As a result, the croaker can monitor and handle multiple situations at once

Outsourced Analysis of Encrypted Graphs in the Cloud with Privacy Protection

Huge diagrams have unique properties for organizations and research, such as client linkages in informal organizations and customer evaluation lattices in social channels. They necessitate a lot of financial assets to maintain because they are large and frequently continue to expand. Owners of large diagrams may need to use cloud resources due to the extensive arrangement of open cloud resources to increase capacity and computation flexibility. However, the cloud's accountability and protection of schematics have become a significant issue. In this study, we consider calculations for security savings for essential graph examination practices: schematic extraterrestrial examination for outsourcing graphs in the cloud server. We create the security-protecting variants of the two proposed Eigen decay computations. They are using two cryptographic algorithms: additional substance homomorphic encryption (ASHE) strategies and some degree homomorphic encryption (SDHE) methods. Inadequate networks also feature a distinctively confidential info adaptation convention to allow the trade-off between secrecy and data sparseness. Both dense and sparse structures are investigated. According to test results, calculations with sparse encoding can drastically reduce information. SDHE-based strategies have reduced computing time, while ASHE-based methods have reduced stockpiling expenses

G359.87+0.18: An FR II Radio Galaxy 15 Arcminutes from Sgr A*. Implications for the Scattering Region in the Galactic Center

G359.87+0.18 is an enigmatic object located 15' from Sgr A*. It has been variously classified as an extragalactic source, Galactic jet source, and young supernova remnant. We present new observations of G359.87+0.18 between 0.33 and 15 GHz and use these to argue that this source is an Faranoff-Riley II radio galaxy. We are able to place a crude limit on its redshift of z > 0.1. The source has a spectral index \alpha < -1 (S \propto \nu^\alpha), suggestive of a radio galaxy with a redshift z >~ 2. The scattering diameters of Sgr A* and several nearby OH masers (~ 1" at 1 GHz) indicate that a region of enhanced scattering is along the line of sight to the Galactic center. If the region covers the Galactic center uniformly, the implied diameter for a background source is at least 600" at 0.33 GHz, in contrast with the observed 20" diameter of G359.87+0.18. Using the scattering diameter of a nearby OH maser OH 359.762+0.120 and the widths of two, nearby, non-thermal threads, G0.08+0.15 and G359.79+0.17, we show that a uniform scattering region should cover G359.87+0.18. We therefore conclude that the Galactic center scattering region is inhomogeneous on a scale of 5' (~ 10 pc at a distance of 8.5 kpc). This scale is comparable to the size scale of molecular clouds in the Galactic center. The close agreement between these two lengths scales is an indication that the scattering region is linked intimately to the Galactic center molecular clouds.Comment: Accepted for publication in the ApJ, vol. 515, LaTeX2e manuscript using aaspp4 macro, 19 pages, 8 figures in 11 PostScript file

Development and application of C - scan ultrasonic facility

This paper presents the in-house development and application of a C-scan ultrasonic facility ULTIMA 200M2 at the Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam, carried out in collaboration with the Electronics Division, Bhabha Atomic Research Centre (BARC), Mumbai. The paper describes various constituents of the system developed and also highlights the typical results obtained using this system, including bond integrity assessment of explosive welds and imaging of fuel sub-assembly heads of the Fast Breeder Test Reactor. The system has also been used for imaging both the sides of a one rupee Indian coin. All the finer details of the coin could be extracted, demonstrating the resolution capabilities of the system

Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells

The 2009 influenza pandemic originated from a swine-origin H1N1 virus, which, although less pathogenic than anticipated, may acquire additional virulence-associated mutations in the future. To estimate the potential risk, we sequentially passaged the isolate A/Hamburg/04/2009 in A549 human lung epithelial cells. After passage 6, we observed a 100-fold increased replication rate. High-throughput sequencing of viral gene segments identified five dominant mutations, whose contribution to the enhanced growth was analyzed by reverse genetics. The increased replication rate was pinpointed to two mutations within the hemagglutinin (HA) gene segment (HA1 D130E, HA2 I91L), near the receptor binding site and the stem domain. The adapted virus also replicated more efficiently in mice in vivo. Enhanced replication rate correlated with increased fusion pH of the HA protein and a decrease in receptor affinity. Our data might be relevant for surveillance of pre-pandemic strains and development of high titer cell culture strains for vaccine production

An 8.5 GHz Arecibo survey of Carbon Recombination Lines toward Ultra-compact \HII regions: Physical properties of dense molecular material

We report here on a survey of carbon recombination lines (RLs) near 8.5 GHz toward 17 ultra-compact \HII regions (\UCHII s). Carbon RLs are detected in 11 directions, indicating the presence of dense photodissociation regions (PDRs) associated with the \UCHII s. In this paper, we show that the carbon RLs provide important, complementary information on the kinematics and physical properties of the ambient medium near \UCHII s. Non-LTE models for the carbon line forming region are developed, assuming that the PDRs surround the \UCHII s, and we constrained the model parameters by multi-frequency RL data. Modeling shows that carbon RL emission near 8.5 GHz is dominated by stimulated emission and hence we preferentially observe the PDR material that is in front of the \UCHII continuum. We find that the relative motion between ionized gas and the associated PDR is about half that estimated earlier, and has an RMS velocity difference of 3.3 \kms. Our models also give estimates for the PDR density and pressure. We found that the neutral density of PDRs is typically $>$ 5 $\times$ 10$^5$ \cmthree and \UCHII s can be embedded in regions with high ambient pressure. Our results are consistent with a pressure confined \HII region model where the stars are moving relative to the cloud core. Other models cannot be ruled out, however. Interestingly, in most cases, the PDR pressure is an order of magnitude larger than the pressure of the ionized gas. Further investigation is needed to understand this large pressure difference.Comment: 28 pages, 7 figures, 5 tables (accepted for publication in ApJ

MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics and Pharmacodynamic Electrophysiology in Experimental Animal Models and in Humans.

BACKGROUND: -We evaluated the viability of I(Kur) as a target for maintenance of sinus rhythm in patients with a history of atrial fibrillation through the testing of MK-0448, a novel I(Kur) inhibitor. METHODS AND RESULTS: -In vitro MK-0448 studies demonstrated strong inhibition of I(Kur) with minimal off-target activity. In vivo MK-0448 studies in normal anesthetized dogs demonstrated significant prolongation of the atrial refractory period compared with vehicle controls without affecting the ventricular refractory period. In studies of a conscious dog heart failure model, sustained AF was terminated with bolus intravenous MK-0448 doses of 0.03 and 0.1 mg/kg. These data led to a two-part first-in-human study: Part I evaluated safety and pharmacokinetics, and Part II was an invasive electrophysiologic (EP) study in healthy subjects. MK-0448 was well-tolerated with mild adverse experiences, most commonly irritation at the injection site. During the EP study, ascending doses of MK-0448 were administered, but no increases in atrial or ventricular refractoriness were detected despite achieving plasma concentrations in excess of 2 μM. Follow-up studies in normal anesthetized dogs designed to assess the influence of autonomic tone demonstrated that prolongation of atrial refractoriness with MK-0448 was markedly attenuated in the presence of vagal nerve simulation, suggesting that the effects of I(Kur) blockade on atrial repolarization may be negated by enhanced parasympathetic neural tone. CONCLUSIONS: -The contribution of I(Kur) to human atrial electrophysiology is less prominent than in preclinical models and therefore is likely to be of limited therapeutic value for the prevention of atrial fibrillation

The Murchison Widefield Array: Design Overview

The Murchison Widefield Array (MWA) is a dipole-based aperture array synthesis telescope designed to operate in the 80-300 MHz frequency range. It is capable of a wide range of science investigations, but is initially focused on three key science projects. These are detection and characterization of 3-dimensional brightness temperature fluctuations in the 21cm line of neutral hydrogen during the Epoch of Reionization (EoR) at redshifts from 6 to 10, solar imaging and remote sensing of the inner heliosphere via propagation effects on signals from distant background sources,and high-sensitivity exploration of the variable radio sky. The array design features 8192 dual-polarization broad-band active dipoles, arranged into 512 tiles comprising 16 dipoles each. The tiles are quasi-randomly distributed over an aperture 1.5km in diameter, with a small number of outliers extending to 3km. All tile-tile baselines are correlated in custom FPGA-based hardware, yielding a Nyquist-sampled instantaneous monochromatic uv coverage and unprecedented point spread function (PSF) quality. The correlated data are calibrated in real time using novel position-dependent self-calibration algorithms. The array is located in the Murchison region of outback Western Australia. This region is characterized by extremely low population density and a superbly radio-quiet environment,allowing full exploitation of the instrumental capabilities.Comment: 9 pages, 5 figures, 1 table. Accepted for publication in Proceedings of the IEE

The Radio Ammonia Mid-plane Survey (RAMPS) Pilot Survey

The Radio Ammonia Mid-Plane Survey (RAMPS) is a molecular line survey that aims to map a portion of the Galactic midplane in the first quadrant of the Galaxy (l = 10°–40°, | b| \leqslant 0\buildrel{\circ}\over{.} 4) using the Green Bank Telescope. We present results from the pilot survey, which has mapped approximately 6.5 square degrees in fields centered at l = 10°, 23°, 24°, 28°, 29°, 30°, 31°, 38°, 45°, and 47°. RAMPS observes the NH3 inversion transitions NH3(1,1)–(5,5), the H2O 61,6–52,3 maser line at 22.235 GHz, and several other molecular lines. We present a representative portion of the data from the pilot survey, including NH3(1,1) and NH3(2,2) integrated intensity maps, H2O maser positions, maps of NH3 velocity, NH3 line width, total NH3 column density, and NH3 rotational temperature. These data and the data cubes from which they were produced are publicly available on the RAMPS website (http://sites.bu.edu/ramps/)